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ANTIBODY
We follow an iterative cycle of design, synthesis, assay, and structural analysis to optimize compounds. During the assay phase we can assess the compound’s activity or drug-like properties such as solubility, providing critical insights into its potential as a drug candidate. Structural analysis explains how the compound can be improved in terms of efficacy, thus informing the next design phase. Our team can execute this entire process or any combination of it and collaborate with you on specific steps, including co-designing compounds to accelerate the drug discovery program.
NJ Bio offers the following Medicinal Chemistry Services
- Design and synthesis of chemical compounds for lead discovery and lead optimization
- Screening, including fragment screening
- Verification of screening hits using BioNMR
- Assays
- Compound scale up, ensuring reliability and reproducibility
- Comprehensive bioanalytical and analytical support
PAYLOAD LINKER
We follow an iterative cycle of design, synthesis, assay, and structural analysis to optimize compounds. During the assay phase we can assess the compound’s activity or drug-like properties such as solubility, providing critical insights into its potential as a drug candidate. Structural analysis explains how the compound can be improved in terms of efficacy, thus informing the next design phase. Our team can execute this entire process or any combination of it and collaborate with you on specific steps, including co-designing compounds to accelerate the drug discovery program.
NJ Bio offers the following Medicinal Chemistry Services
- Design and synthesis of chemical compounds for lead discovery and lead optimization
- Screening, including fragment screening
- Verification of screening hits using BioNMR
- Assays
- Compound scale up, ensuring reliability and reproducibility
- Comprehensive bioanalytical and analytical support
Bioconjugation Discovery
We follow an iterative cycle of design, synthesis, assay, and structural analysis to optimize compounds. During the assay phase we can assess the compound’s activity or drug-like properties such as solubility, providing critical insights into its potential as a drug candidate. Structural analysis explains how the compound can be improved in terms of efficacy, thus informing the next design phase. Our team can execute this entire process or any combination of it and collaborate with you on specific steps, including co-designing compounds to accelerate the drug discovery program.
NJ Bio offers the following Medicinal Chemistry Services
- Design and synthesis of chemical compounds for lead discovery and lead optimization
- Screening, including fragment screening
- Verification of screening hits using BioNMR
- Assays
- Compound scale up, ensuring reliability and reproducibility
- Comprehensive bioanalytical and analytical support
Drug Substance (DS) Process Development
We follow an iterative cycle of design, synthesis, assay, and structural analysis to optimize compounds. During the assay phase we can assess the compound’s activity or drug-like properties such as solubility, providing critical insights into its potential as a drug candidate. Structural analysis explains how the compound can be improved in terms of efficacy, thus informing the next design phase. Our team can execute this entire process or any combination of it and collaborate with you on specific steps, including co-designing compounds to accelerate the drug discovery program.
NJ Bio offers the following Medicinal Chemistry Services
- Design and synthesis of chemical compounds for lead discovery and lead optimization
- Screening, including fragment screening
- Verification of screening hits using BioNMR
- Assays
- Compound scale up, ensuring reliability and reproducibility
- Comprehensive bioanalytical and analytical support
Formulation and Drug Product (DP) Development
We follow an iterative cycle of design, synthesis, assay, and structural analysis to optimize compounds. During the assay phase we can assess the compound’s activity or drug-like properties such as solubility, providing critical insights into its potential as a drug candidate. Structural analysis explains how the compound can be improved in terms of efficacy, thus informing the next design phase. Our team can execute this entire process or any combination of it and collaborate with you on specific steps, including co-designing compounds to accelerate the drug discovery program.
NJ Bio offers the following Medicinal Chemistry Services
- Design and synthesis of chemical compounds for lead discovery and lead optimization
- Screening, including fragment screening
- Verification of screening hits using BioNMR
- Assays
- Compound scale up, ensuring reliability and reproducibility
- Comprehensive bioanalytical and analytical support
Analytical Development
We follow an iterative cycle of design, synthesis, assay, and structural analysis to optimize compounds. During the assay phase we can assess the compound’s activity or drug-like properties such as solubility, providing critical insights into its potential as a drug candidate. Structural analysis explains how the compound can be improved in terms of efficacy, thus informing the next design phase. Our team can execute this entire process or any combination of it and collaborate with you on specific steps, including co-designing compounds to accelerate the drug discovery program.
NJ Bio offers the following Medicinal Chemistry Services
- Design and synthesis of chemical compounds for lead discovery and lead optimization
- Screening, including fragment screening
- Verification of screening hits using BioNMR
- Assays
- Compound scale up, ensuring reliability and reproducibility
- Comprehensive bioanalytical and analytical support
DS Manufacturing
We follow an iterative cycle of design, synthesis, assay, and structural analysis to optimize compounds. During the assay phase we can assess the compound’s activity or drug-like properties such as solubility, providing critical insights into its potential as a drug candidate. Structural analysis explains how the compound can be improved in terms of efficacy, thus informing the next design phase. Our team can execute this entire process or any combination of it and collaborate with you on specific steps, including co-designing compounds to accelerate the drug discovery program.
NJ Bio offers the following Medicinal Chemistry Services
- Design and synthesis of chemical compounds for lead discovery and lead optimization
- Screening, including fragment screening
- Verification of screening hits using BioNMR
- Assays
- Compound scale up, ensuring reliability and reproducibility
- Comprehensive bioanalytical and analytical support
DP Manufacturing
We follow an iterative cycle of design, synthesis, assay, and structural analysis to optimize compounds. During the assay phase we can assess the compound’s activity or drug-like properties such as solubility, providing critical insights into its potential as a drug candidate. Structural analysis explains how the compound can be improved in terms of efficacy, thus informing the next design phase. Our team can execute this entire process or any combination of it and collaborate with you on specific steps, including co-designing compounds to accelerate the drug discovery program.
NJ Bio offers the following Medicinal Chemistry Services
- Design and synthesis of chemical compounds for lead discovery and lead optimization
- Screening, including fragment screening
- Verification of screening hits using BioNMR
- Assays
- Compound scale up, ensuring reliability and reproducibility
- Comprehensive bioanalytical and analytical support
Frequently Asked Questions (FAQs)
Can you assist with early-stage drug development?
Yes, we offer support at all stages, from initial hit identification to lead optimization and preclinical development.
Do you provide custom synthesis of specific chemical compounds?
We specialize in custom synthesis tailored to your specific project requirements, including complex molecules and their analogs.
Do you provide support for in vitro testing? What type of bioassays do you perform?
Yes, we offer extensive support for in vitro testing through our advanced bioanalytical and analytical platforms, specifically designed for small molecule drug evaluation. We can assist with a variety of assays, including binding assays and cellular assays. For more information visit https://njbio.com/bioanalytical-services-for-adcs-and-other-bioconjugates/
Do you perform advanced BioNMR studies?
Our BioNMR findings are used for compound design, optimization of lead candidates and studying target interactions. We also perform advanced BioNMR studies such as multi-dimensional NMR in our ‘Centre for NMR Excellence’. To know more visit https://njbio.com/bio-nmr-services/