Protoxins for ADC

Protoxins for ADC Icon
NJ Bio is developing Protoxins for antibody-drug conjugates (ADCs). Three different types of Protoxins are being studied.
  • Type 1: Targeted Protein Degrader Protoxins
  • Type 2: Reversible Protoxins (Prodrug type)
    • Active in cancer cell environment and inactive in normal tissues
  • Type 3: Non-Reversible Protoxins (non-reversible Prodrug type)
    • Protoxins get converted to toxin metabolites in cancer cell line

Advantages of Protoxins
  • Increased safety and toxicity profile
  • Better stability
  • Compatible with wide variety of linkers and conjugation methods

For more detail, please contact us at
NJ Bio’s proprietary toxins for ADCs