info@njbio.com
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350 Carter Rd, Princeton, NJ 08540
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NJ Bio is developing Protoxins for antibody-drug conjugates (ADCs). Three different types of Protoxins are being studied.
- Type 1: Targeted Protein Degrader Protoxins
- Type 2: Reversible Protoxins (Prodrug type)
- Active in cancer cell environment and inactive in normal tissues
- Type 3: Non-Reversible Protoxins (non-reversible Prodrug type)
- Protoxins get converted to toxin metabolites in cancer cell line
Advantages of Protoxins
- Increased safety and toxicity profile
- Better stability
- Compatible with wide variety of linkers and conjugation methods
For more detail, please contact us at info@njbio.com.