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Publications by NJ Bio’s Team Members

Best Contract Research Provider Winner 2021

Antibody-Drug Conjugates – Selected Publications by NJ Bio’s Team Members
(The names of NJ Bio’s team members are marked in Bold)

Akaiwa, M.; Dugal-Tessier, J.; Mendelsohn, B. A. “Antibody-Drug Conjugate Payloads; Study of Auristatin Derivatives” Chem. Pharm. Bull. 2020, 68, 201–211. https://doi.org/10.1248/cpb.c19-00853

Snyder, J. T.; Malinao, M-C.; Dugal-Tessier, J.; Atkinson, J. E.; Anand, B. S.; Okada, A.; Mendelsohn, B. A. “Metabolism of an Oxime-Linked Antibody Drug Conjugate, AGS62P1, and Characterization of Its Identified Metabolite” Molecular Pharm. 2018, 15, 2384–2390. https://doi.org/10.1021/acs.molpharmaceut.8b00225

Thirumalairajan, S.; Novak, J.; Ghone, S. “QbD in the Development of ADCs with PBD Dimer Warheads” BioPharm. International, 2018, 31 (9), 30–35. http://www.biopharminternational.com/qbd-development-adcs-pbd-dimer-warheads

Nittoli, T.; Giurleo, J.; Papadopoulos, N.; Chen, Z.; Markotan, T. P.; Delfino, F.; Thurston, G.; Kelly, M.; Shan, J.; Jiang, X.; Navarro, E.; Kirshner, J. R.; Kunz, A.; Hickey, C.; Spink, J.; Zhao, F.; Tait, M.; Hylton, D.; Rudge, J.; Makonnen, S.; Provoncha, K.Antibody Drug Conjugates of Cleavable Amino-alkyl and Aryl Maytansinoids” Bioorg. Med. Chem. 2018, 26, 2271–79. https://doi.org/10.1016/j.bmc.2018.02.025

Smith, S. W.; Jammalamadaka, V.; Borkin, D.; Zhu, J.; Degrado, S. J.; Lu, J.; Huang, J.; Jiang, Y.-P.; Jain, N.; Junutula, J. R. “Design and Synthesis of Isoquinolidinobenzodiazepine Dimers, a Novel Class of Antibody–Drug Conjugate Payload” ACS Med. Chem. Let. 2018, 9, 56–60. https://doi.org/10.1021/acsmedchemlett.7b00436

Jain, N.; Smith, S. W.; Ghone, S.; Tomczuk, B. “Current ADC Linker Chemistry” Pharm. Res. 2015, 32, 3526–3540. doi: 10.1007/s11095-015-1657-7